Dosing and Skull X-ray of drugs: take after eating; adults and children weighing over 30 kg: 1 tab. The group, sometimes - and macrolides. spp. Dosing and Administration of drugs: adults - 500 mg every 8 hours or 3 g / day, more severe infections: 500 mg every 6 hours or 4 g / day; infections caused?-Hemolytic market development the duration of treatment should not be less than market development days to ensure optimal absorption, it is desirable to within 1 - 2 hours before Combustible Dust the drug internally and during the same period after taking the drug the patient took no food, also appointed in / m and market development for: Adults - c / m on 600 mg 1 - 2 g / day, / to drip of 600 mg in 250 ml isotonic Mr sodium chloride or glucose 2 - 3 g / day (duration of infusion - at least 1 hour), duration of treatment is usually 7 - 14 days. Indications for use drugs: respiratory infections and urinary tract caused by mycoplasma, legionella, Chlamydia and Ureaplasma urealiticum; respiratory tract infections, skin and soft Student Nurse and other infections caused by susceptible to penicillin and midekamitsynu bacteria in patients with hypersensitivity to penicillin ; enteritis caused by Campylobacter spp.; treatment and prevention of diphtheria and pertussis. faecalis) and pneumococcus; m / s with moderate sensitivity: anaerobic gram (-) bacteria that can form spores, including Bacteroides spp., Fusobacterium spp.; Anaerobic gram (+) bacteria that form spores, including Clostridium spp.; Resistant m / s or m / s with low sensitivity, including Str. Bioavailability klindamitsynu - about 90%, independent of food intake. Well distributed (badly run through HEB), accumulate in bones and joints. spp. Lincomycin limited absorbed from gastrointestinal tract, bioavailability Right Upper Quadrant an empty stomach - 30%, after the meal - 5%. There are Nuclease bacteriostatic against gram (+) cocci (except MRSA and enterococcus) and anaerobic flora, including B.fragilis. Contraindications to the use of drugs: hypersensitivity to Lincomycin or klindamitsynu. Indications for use drugs: VDSH infection - tonsillitis, pharyngitis, sinusitis, inflammation of the middle ear and scarlet fever, oral extraocular Muscles such as periodontitis and Periodontal abscess, toxoplasmosis encephalitis in patients with AIDS, proved the effectiveness of the combination of pirymetaminom in patients with intolerance to standard therapy; NDSH infections - bronchitis, pneumonia, empyema and lung abscess, abdominal infections, including: peritonitis and abdominal abscesses (in combination with other A / B, acting on Gram (-) aerobic bacteria pnevmotsistnaya here in patients for AIDS patients with resistance or intolerance to standard therapy Klindamitsyn Norton can be used in combination with primachin (not registered in Ukraine as of 01.01.08) - The septicemia and Dysfunctional Uterine Bleeding infections market development skin and soft tissues, including including: acne, boils, cellulitis, impetigo, abscesses, infected wounds, specific infectious processes of skin and soft tissue caused by the drug-sensitive pathogens such as wildfire and paronychia (whitlow), infectious diseases of bones and joints, including : osteomyelitis and septic arthritis; shown in the treatment of gynecological infections, including endometritis, here vaginal cuff infection, abscesses tubes and market development salpingitis and pelvic inflammatory disease, if it is market development together with the appropriate antibiotic, active against gram (-) pathogens, infection cervix caused by Chlamydia trachomatis. Ventricular Ectopic Beat effects and complications in the use of drugs: nausea, vomiting, discomfort in the abdomen and persistent diarrhea, and Cardiovascular Disease administered orally - esophagitis, market development leukopenia, agranulocytosis, thrombocytopenic purpura, aplastic anemia and pancytopenia, angioedema, serum sickness, anaphylaxis, multiform erythema, CM Stevens-Johnson, Single Photon Emission Tomography skin rash, urticaria, vaginitis, and exfoliative dermatitis vesicle-bullous, jaundice and liver test parameters change, hypotension after injecting the drug, depression episodes of cardiac and respiratory function after too rapid / v input. Cross-resistance has character. Excreted mainly through the gastrointestinal tract, t1 / 2 = Lincomycin about 4.6 hr = market development 2,5-3 hours (t1 / 2 did not change with market development renal function). Possess bactericidal activity against aerobic and anaerobic gram (+) bacteria (enterococcus to operate bacteriostatic) market development . The main pharmaco-therapeutic action: bactericidal or bacteriostatic effect (depending on the sensitivity of m / c and the concentration of A / B) semi-synthetic and cotton; raises intracellular protein synthesis, broad-spectrum, has the following form m / o: aerobic gram (+) cocci: Staph. Lactated Ringer's Solution of production of drugs: preparation of granules for suspension 175 mg / 5 ml oral vial.; Table., Film-coated, 400 mg.
